• Immunofluorescence analysis of A549 cells using ETV1 antibody (STJ115267).
  • Immunohistochemistry analysis of paraffin-embedded mouse pancreas using ETV1 antibody (STJ115267) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human breast cancer using ETV1 antibody (STJ115267) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded rat pancreas using ETV1 antibody (STJ115267) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-ETV1 antibody (80-300) (STJ115267)

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STJ115267

£112.50 - £522.50
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Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ETV1 (80-300) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ETV1
Gene ID: 2115
Uniprot ID: ETV1_HUMAN
Immunogen Region: 80-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-300 of human ETV1 (NP_004947.2).
Immunogen Sequence: AFHGLPLKIKKEPHSPCSEI SSACSQEQPFKFSYGEKCLY NVSAYDQKPQVGMRPSNPPT PSSTPVSPLHHASPNSTHTP KPDRAFPAHLPPSQSIPDSS YPMDHRFRRQLSEPCNSFPP LPTMPREGRPMYQRQMSEPN IPFPPQGFKQEYHDPVYEHN TMVGSAASQSFPPPLMIKQE PRDFAYDSEVPSCHSIYMRQ EGFLAHPSRTEGCMFEKGPR Q
Tissue Specificity Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
Post Translational Modifications Sumoylated. Phosphorylated at Ser-191 and Ser-216 by RPS6KA1 and RPS6KA5.phosphorylation activates transcriptional activity.
Function Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGAAT-3'. Required for olfactory dopaminergic neuron differentiation.may directly activate expression of tyrosine hydroxylase (TH).
Protein Name Ets Translocation Variant 1
Ets-Related Protein 81
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Ets Translocation Variant 1 antibody
Anti-Ets-Related Protein 81 antibody
Anti-ETV1 antibody
Anti-ER81 antibody

Information sourced from Uniprot.org

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