Anti-ETAA1 antibody (STJ190815)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Ewing s tumor-associated antigen 1 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ETAA1 |
| Gene ID | 54465 |
| Uniprot ID | ETAA1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | ETAA1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by ATR. |
| Function | Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity. Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1. Probably only regulates a subset of ATR targets. |
| Protein Name | Ewing's Tumor-Associated Antigen 1Ewing's Tumor-Associated Antigen 16 |
| Database Links | |
| Cellular Localisation | NucleusLocalizes At Sites Of Dna Damage Following Replication StressRecruited To Stalled Replication Forks Via Interaction With Rpa1 And Rpa2 Subunits Of The Rpa Complex |
| Alternative Antibody Names | Anti-Ewing's Tumor-Associated Antigen 1 antibodyAnti-Ewing's Tumor-Associated Antigen 16 antibodyAnti-ETAA1 antibodyAnti-ETAA16 antibody |
Information sourced from Uniprot.org