Anti-ESYT2 antibody (STJA0008736)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human FAM62B
General Information
| Short Description | Rabbit polyclonal anti-Extended synaptotagmin-2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ESYT2 |
| Gene ID | 57488 |
| Uniprot ID | ESYT2_HUMAN |
| Immunogen | Synthesized peptide derived from human FAM62B |
| Specificity | This antibody detects endogenous levels of FAM62B at Human, Mouse |
Additional Info
| Function | Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding.this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS). |
| Protein Name | Extended Synaptotagmin-2E-Syt2Chr2syt |
| Database Links | Reactome: R-HSA-9845576 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneMulti-Pass Membrane ProteinLocalizes To Endoplasmic Reticulum-Plasma Membrane Contact Sites (Epcs)Recruited To The Cell Membrane Via The Third C2 Domain |
| Alternative Antibody Names | Anti-Extended Synaptotagmin-2 antibodyAnti-E-Syt2 antibodyAnti-Chr2syt antibodyAnti-ESYT2 antibodyAnti-FAM62B antibodyAnti-KIAA1228 antibody |
Information sourced from Uniprot.org