Anti-ESRRG antibody (400-458) {FITC} (STJ500968)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 400-458 on human Estrogen-related receptor gamma/ERR3 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-ESRRG (400-458) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.5-1.5 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ESRRG |
| Gene ID | 2104 |
| Uniprot ID | ERR3_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 400-458 on human Estrogen-related receptor gamma/ERR3 protein. |
| Immunogen Region | 400-458 |
Additional Info
| Post Translational Modifications | Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity. |
| Function | Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle. |
| Protein Name | Estrogen-Related Receptor GammaErr Gamma-2Estrogen Receptor-Related Protein 3Nuclear Receptor Subfamily 3 Group B Member 3 |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Estrogen-Related Receptor Gamma antibodyAnti-Err Gamma-2 antibodyAnti-Estrogen Receptor-Related Protein 3 antibodyAnti-Nuclear Receptor Subfamily 3 Group B Member 3 antibodyAnti-ESRRG antibodyAnti-ERR3 antibodyAnti-ERRG2 antibodyAnti-KIAA0832 antibodyAnti-NR3B3 antibody |
Information sourced from Uniprot.org