Anti-ESRRG antibody (400-458) {FITC} (STJ500968)

SKU:
STJ500968-100

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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ESRRG (400-458) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:2, 500-1:5, 000
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ESRRG
Gene ID: 2104
Uniprot ID: ERR3_HUMAN
Immunogen Region: 400-458
Immunogen: Synthetic peptide taken within amino acid region 400-458 on human Estrogen-related receptor gamma/ERR3 protein.
Post Translational Modifications Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.
Function Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle.
Protein Name Estrogen-Related Receptor Gamma
Err Gamma-2
Estrogen Receptor-Related Protein 3
Nuclear Receptor Subfamily 3 Group B Member 3
Database Links Reactome: R-HSA-383280
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Estrogen-Related Receptor Gamma antibody
Anti-Err Gamma-2 antibody
Anti-Estrogen Receptor-Related Protein 3 antibody
Anti-Nuclear Receptor Subfamily 3 Group B Member 3 antibody
Anti-ESRRG antibody
Anti-ERR3 antibody
Anti-ERRG2 antibody
Anti-KIAA0832 antibody
Anti-NR3B3 antibody

Information sourced from Uniprot.org

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