| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-ESRRG (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S2MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ESRRG |
| Gene ID: |
2104 |
| Uniprot ID: |
ERR3_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ESRRG (P62508). |
| Immunogen Sequence: |
MDSVELCLPESFSLHYEEEL LCRMSNKDRHIDSSCSSFIK TEPSSPASLTDSVNHHSPGG SSDASGSYSSTMNGHQNGLD SPPLYPSAPILGGSGPVRKL |
| Tissue Specificity | Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland. |
| Post Translational Modifications | Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity. |
| Function | Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle. |
| Protein Name | Estrogen-Related Receptor GammaErr Gamma-2Estrogen Receptor-Related Protein 3Nuclear Receptor Subfamily 3 Group B Member 3 |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Estrogen-Related Receptor Gamma antibodyAnti-Err Gamma-2 antibodyAnti-Estrogen Receptor-Related Protein 3 antibodyAnti-Nuclear Receptor Subfamily 3 Group B Member 3 antibodyAnti-ESRRG antibodyAnti-ERR3 antibodyAnti-ERRG2 antibodyAnti-KIAA0832 antibodyAnti-NR3B3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
