| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Steroid hormone receptor ERR1 (160-240 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ESRRA |
| Gene ID: | 2101 |
| Uniprot ID: | ERR1_HUMAN |
| Immunogen Region: | 160-240 aa |
| Specificity: | ERR1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 160-240 |
| Function | Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. |
| Protein Name | Steroid Hormone Receptor Err1 Estrogen Receptor-Like 1 Estrogen-Related Receptor Alpha Err-Alpha Nuclear Receptor Subfamily 3 Group B Member 1 |
| Database Links | Reactome: R-HSA-1989781 Reactome: R-HSA-2151201 Reactome: R-HSA-383280 Reactome: R-HSA-8939902 |
| Cellular Localisation | Nucleus Cytoplasm Co-Localizes To The Cytoplasm Only In Presence Of Mapk15 |
| Alternative Antibody Names | Anti-Steroid Hormone Receptor Err1 antibody Anti-Estrogen Receptor-Like 1 antibody Anti-Estrogen-Related Receptor Alpha antibody Anti-Err-Alpha antibody Anti-Nuclear Receptor Subfamily 3 Group B Member 1 antibody Anti-ESRRA antibody Anti-ERR1 antibody Anti-ESRL1 antibody Anti-NR3B1 antibody |
Information sourced from Uniprot.org