Anti-Erythropoietin/EPO antibody (28-193aa) [AT1C12] (STJA0041885)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human Erythropoietin (28-193aa) purified from insect cell
General Information
| Short Description | Mouse monoclonal anti-Erythropoietin/EPO (28-193aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT1C12 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EPO |
| Gene ID | 2056 |
| Uniprot ID | EPO_HUMAN |
| Accession Number | NP_000790 |
| Immunogen | Recombinant human Erythropoietin (28-193aa) purified from insect cell |
| Immunogen Region | 28-193aa |
Additional Info
| Tissue Specificity | Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. |
| Function | Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. |
| Protein Name | ErythropoietinEpoetin |
| Database Links | Reactome: R-HSA-1234158Reactome: R-HSA-9006335Reactome: R-HSA-9027276Reactome: R-HSA-9027277Reactome: R-HSA-9027283Reactome: R-HSA-9027284 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Erythropoietin antibodyAnti-Epoetin antibodyAnti-EPO antibody |
Information sourced from Uniprot.org