Anti-EPSTI1 antibody (STJA0004669)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human EPSTI1
General Information
| Short Description | Rabbit polyclonal anti-Epithelial-Stromal Interaction Protein 1 for use in IHC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.66 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:30-1:150 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | EPSTI1 |
| Gene ID | 94240 |
| Uniprot ID | ESIP1_HUMAN |
| Immunogen | Synthetic peptide of human EPSTI1 |
Additional Info
| Tissue Specificity | Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vitro. Expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE). |
| Function | Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation. Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages. |
| Protein Name | Epithelial-Stromal Interaction Protein 1 |
| Database Links | Reactome: R-HSA-9696273 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Epithelial-Stromal Interaction Protein 1 antibodyAnti-EPSTI1 antibody |
Information sourced from Uniprot.org