Anti-Epsin 1 antibody [SRM13086] (STJ11107816)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal Epsin-1 antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM13086 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:100-1:500ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EPN1 |
| Gene ID | 29924 |
| Uniprot ID | EPN1_HUMAN |
| Immunogen | Synthetic peptide. This information is considered to be commercially sensitive. |
| Immunogen Sequence | Human |
Additional Info
| Function | Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis. |
| Protein Name | Epsin-1Eh Domain-Binding Mitotic PhosphoproteinEps-15-Interacting Protein 1 |
| Database Links | Reactome: R-HSA-182971Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinNucleusMembraneClathrin-Coated PitAssociated With The Cytoplasmic Membrane At Sites Where Clathrin-Coated Pits Are FormingColocalizes With Clathrin And Ap-2 In A Punctate Pattern On The Plasma MembraneDetected In Presynaptic Nerve Terminals And In Golgi StacksMay Shuttle To The Nucleus When Associated With Zbtb16/Znf145 |
| Alternative Antibody Names | Anti-Epsin-1 antibodyAnti-Eh Domain-Binding Mitotic Phosphoprotein antibodyAnti-Eps-15-Interacting Protein 1 antibodyAnti-EPN1 antibody |
Information sourced from Uniprot.org