Anti-EPO antibody (93-193) (STJ27630)

Name: Anti-EPO antibody (93-193) (STJ27630)
SKU: STJ27630
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ27630

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Short Description	Rabbit polyclonal EPO (93-193) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:100-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	EPO
Gene ID	2056
Uniprot ID	EPO_HUMAN
Immunogen Region	93-193
Immunogen Sequence	GLALLSEAVLRGQALLVNSS QPWEPLQLHVDKAVSGLRSL TTLLRALGAQKEAISPPDAA SAAPLRTITADTFRKLFRVY SNFLRGKLKLYTGEACRTGD R
Specificity	A synthetic peptide corresponding to a sequence within amino acids 93-193 of human EPO (NP_000790.2).

Tissue Specificity	Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
Function	Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
Protein Name	Erythropoietin Epoetin
Database Links	Reactome: R-HSA-1234158 Reactome: R-HSA-9006335 Reactome: R-HSA-9027276 Reactome: R-HSA-9027277 Reactome: R-HSA-9027283 Reactome: R-HSA-9027284
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Erythropoietin antibody Anti-Epoetin antibody Anti-EPO antibody

Information sourced from Uniprot.org