Anti-EPN1 antibody [SAA1730] (STJA0020158)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Epsin-1 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1730 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | EPN1 |
| Gene ID | 29924 |
| Uniprot ID | EPN1_HUMAN |
Additional Info
| Function | Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis. |
| Protein Name | Epsin-1Eh Domain-Binding Mitotic PhosphoproteinEps-15-Interacting Protein 1 |
| Database Links | Reactome: R-HSA-182971Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinNucleusMembraneClathrin-Coated PitAssociated With The Cytoplasmic Membrane At Sites Where Clathrin-Coated Pits Are FormingColocalizes With Clathrin And Ap-2 In A Punctate Pattern On The Plasma MembraneDetected In Presynaptic Nerve Terminals And In Golgi StacksMay Shuttle To The Nucleus When Associated With Zbtb16/Znf145 |
| Alternative Antibody Names | Anti-Epsin-1 antibodyAnti-Eh Domain-Binding Mitotic Phosphoprotein antibodyAnti-Eps-15-Interacting Protein 1 antibodyAnti-EPN1 antibody |
Information sourced from Uniprot.org