![Anti-EPHX2 nanobody [SAA1372] (STJN000204)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200817/412999/STJN000204-SDS-PAGE-1__37745.1749232520.jpg?c=1 "Anti-EPHX2 nanobody [SAA1372] (STJN000204)")
![Anti-EPHX2 nanobody [SAA1372] (STJN000204)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200817/412999/STJN000204-SDS-PAGE-1__37745.1749232520.jpg?c=1 "Anti-EPHX2 nanobody [SAA1372] (STJN000204)")
Anti-EPHX2 nanobody [SAA1372] (STJN000204)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Bifunctional Epoxide Hydrolase 2 Includes-Cytosolic Epoxide Hydrolase 2 is suitable for use in ELISA research applications. |
| Applications | ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1372 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | EPHX2 |
| Gene ID | 2053 |
| Uniprot ID | HYES_HUMAN |
Additional Info
| Function | Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. Bifunctional enzyme. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid. Has phosphatase activity toward lyso-glycerophospholipids with also some lower activity toward lysolipids of sphingolipid and isoprenoid phosphates. |
| Protein Name | Bifunctional Epoxide Hydrolase 2 Includes - Cytosolic Epoxide Hydrolase 2CehEpoxide HydrataseSoluble Epoxide HydrolaseSeh - Lipid-Phosphate Phosphatase |
| Database Links | Reactome: R-HSA-2142670Reactome: R-HSA-9018682Reactome: R-HSA-9033241 |
| Cellular Localisation | CytoplasmPeroxisome |
| Alternative Nanobody Names | Anti-Bifunctional Epoxide Hydrolase 2 Includes - Cytosolic Epoxide Hydrolase 2 nanobodyAnti-Ceh nanobodyAnti-Epoxide Hydratase nanobodyAnti-Soluble Epoxide Hydrolase nanobodyAnti-Seh - Lipid-Phosphate Phosphatase nanobodyAnti-EPHX2 nanobody |
Information sourced from Uniprot.org