Anti-EPHX2 antibody (STJA0007295)

SKU:
STJA0007295

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Bifunctional epoxide hydrolase 2 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EPHX2
Gene ID: 2053
Uniprot ID: HYES_HUMAN
Specificity: This antibody detects endogenous levels of EPHX2 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human EPHX2
Function Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. Bifunctional enzyme. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid. Has phosphatase activity toward lyso-glycerophospholipids with also some lower activity toward lysolipids of sphingolipid and isoprenoid phosphates.
Protein Name Bifunctional Epoxide Hydrolase 2 Includes - Cytosolic Epoxide Hydrolase 2
Ceh
Epoxide Hydratase
Soluble Epoxide Hydrolase
Seh - Lipid-Phosphate Phosphatase
Database Links Reactome: R-HSA-2142670
Reactome: R-HSA-9018682
Reactome: R-HSA-9033241
Cellular Localisation Cytoplasm
Peroxisome
Alternative Antibody Names Anti-Bifunctional Epoxide Hydrolase 2 Includes - Cytosolic Epoxide Hydrolase 2 antibody
Anti-Ceh antibody
Anti-Epoxide Hydratase antibody
Anti-Soluble Epoxide Hydrolase antibody
Anti-Seh - Lipid-Phosphate Phosphatase antibody
Anti-EPHX2 antibody

Information sourced from Uniprot.org

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