Anti-EPHX2 antibody (STJA0007295)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human EPHX2
General Information
| Short Description | Rabbit polyclonal anti-Bifunctional epoxide hydrolase 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EPHX2 |
| Gene ID | 2053 |
| Uniprot ID | HYES_HUMAN |
| Immunogen | Synthesized peptide derived from human EPHX2 |
| Specificity | This antibody detects endogenous levels of EPHX2 at Human, Mouse, Rat |
Additional Info
| Function | Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. Bifunctional enzyme. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid. Has phosphatase activity toward lyso-glycerophospholipids with also some lower activity toward lysolipids of sphingolipid and isoprenoid phosphates. |
| Protein Name | Bifunctional Epoxide Hydrolase 2 Includes - Cytosolic Epoxide Hydrolase 2CehEpoxide HydrataseSoluble Epoxide HydrolaseSeh - Lipid-Phosphate Phosphatase |
| Database Links | Reactome: R-HSA-2142670Reactome: R-HSA-9018682Reactome: R-HSA-9033241 |
| Cellular Localisation | CytoplasmPeroxisome |
| Alternative Antibody Names | Anti-Bifunctional Epoxide Hydrolase 2 Includes - Cytosolic Epoxide Hydrolase 2 antibodyAnti-Ceh antibodyAnti-Epoxide Hydratase antibodyAnti-Soluble Epoxide Hydrolase antibodyAnti-Seh - Lipid-Phosphate Phosphatase antibodyAnti-EPHX2 antibody |
Information sourced from Uniprot.org