Anti-EPHA6 antibody (891-940 aa) (STJ92945)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human EPHA6 at the amino acid range 891-940
General Information
| Short Description | Rabbit polyclonal anti-Ephrin type-A receptor 6 (891-940 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EPHA6 |
| Gene ID | 285220 |
| Uniprot ID | EPHA6_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human EPHA6 at the amino acid range 891-940 |
| Immunogen Region | 891-940 aa |
| Specificity | EphA6 Polyclonal Antibody detects endogenous levels of EphA6 protein. |
Additional Info
| Function | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
| Protein Name | Ephrin Type-A Receptor 6Eph Homology Kinase 2Ehk-2Eph-Like Kinase 12Ek12 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Ephrin Type-A Receptor 6 antibodyAnti-Eph Homology Kinase 2 antibodyAnti-Ehk-2 antibodyAnti-Eph-Like Kinase 12 antibodyAnti-Ek12 antibodyAnti-EPHA6 antibodyAnti-EHK2 antibodyAnti-HEK12 antibody |
Information sourced from Uniprot.org