Anti-EP1 receptor/PTGER1 antibody (Internal) (STJ70880)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-EP1 receptor/PTGER1 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.IHC: In paraffin embedded Human Kidney shows membranous staining in the epithelial cells of DCT. Recommended concentration: 1-2ยตg/ml. Paraffin embedded Human Spleen. Recommended concentra |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PTGER1 |
| Gene ID | 5731 |
| Uniprot ID | PE2R1_HUMAN |
| Accession Number | NP_000946.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | DSRRRWGAHGPRS |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. |
| Protein Name | Prostaglandin E2 Receptor Ep1 SubtypePge Receptor Ep1 SubtypePge2 Receptor Ep1 SubtypeProstanoid Ep1 Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prostaglandin E2 Receptor Ep1 Subtype antibodyAnti-Pge Receptor Ep1 Subtype antibodyAnti-Pge2 Receptor Ep1 Subtype antibodyAnti-Prostanoid Ep1 Receptor antibodyAnti-PTGER1 antibody |
Information sourced from Uniprot.org