| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Eomesodermin homolog (59-108 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EOMES |
| Gene ID: | 8320 |
| Uniprot ID: | EOMES_HUMAN |
| Immunogen Region: | 59-108 aa |
| Specificity: | EOMES Polyclonal Antibody detects endogenous levels of EOMES protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human EOMES at the amino acid range 59-108 |
| Function | Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. |
| Protein Name | Eomesodermin Homolog T-Box Brain Protein 2 T-Brain-2 Tbr-2 |
| Database Links | Reactome: R-HSA-9733709 Reactome: R-HSA-9754189 Reactome: R-HSA-9758919 Reactome: R-HSA-9823730 Reactome: R-HSA-9827857 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Eomesodermin Homolog antibody Anti-T-Box Brain Protein 2 antibody Anti-T-Brain-2 antibody Anti-Tbr-2 antibody Anti-EOMES antibody Anti-TBR2 antibody |
Information sourced from Uniprot.org