| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-EOMES (463-686) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EOMES |
| Gene ID: |
8320 |
| Uniprot ID: |
EOMES_HUMAN |
| Immunogen Region: |
463-686 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 463-686 of human EOMES (NP_005433.2). |
| Immunogen Sequence: |
QIVPGGRYGVQSFFPEPFVN TLPQARYYNGERTVPQTNGL LSPQQSEEVANPPQRWLVTP VQQPGTNKLDISSYESEYTS STLLPYGIKSLPLQTSHALG YYPDPTFPAMAGWGGRGSYQ RKMAAGLPWTSRTSPTVFSE DQLSKEKVKEEIGSSWIETP PSIKSLDSNDSGVYTSACKR RRLSPSNSSNENSPSIKCED INAEEYSKDTSKGMGGYYAF YTTP |
| Tissue Specificity | Expressed in CD8+ T-cells. |
| Function | Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. |
| Protein Name | Eomesodermin HomologT-Box Brain Protein 2T-Brain-2Tbr-2 |
| Database Links | Reactome: R-HSA-9733709Reactome: R-HSA-9754189Reactome: R-HSA-9758919Reactome: R-HSA-9823730Reactome: R-HSA-9827857 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Eomesodermin Homolog antibodyAnti-T-Box Brain Protein 2 antibodyAnti-T-Brain-2 antibodyAnti-Tbr-2 antibodyAnti-EOMES antibodyAnti-TBR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
