| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ENTPD2 |
| Gene ID: | 954 |
| Uniprot ID: | ENTP2_HUMAN |
| Immunogen Region: | 28-268 |
| Immunogen Sequence: | PTRDVREPPALKYGIVLDAG SSHTSMFIYKWPADKENDTG IVGQHSSCDVPGGGISSYAD NPSGASQSLVGCLEQALQDV PKERHAGTPLYLGATAGMRL LNLTNPEASTSVLMAVTHTL TQYPFDFRGARILSGQEEGV FGWVTANYLLENFIKYGWVG RWFRPRKGTLGAMDLGGAST QITFETTSPAEDRASEVQLH LYGQHYRVYTHSFLCYGRDQ VLQRLLASALQTHGFHPCW |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-268 of human ENTPD2 (NP_982293.1). |
| Tissue Specificity | Brain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes. |
| Function | In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. |
| Protein Name | Ectonucleoside Triphosphate Diphosphohydrolase 2Ntpdase 2Cd39 Antigen-Like 1Ecto-Atp Diphosphohydrolase 2Ecto-Atpdase 2Ecto-Atpase 2 |
| Database Links | Reactome: R-HSA-8850843 |
| Cellular Localisation | Isoform Long: Cell MembraneMulti-Pass Membrane ProteinIsoform Short: Endoplasmic Reticulum MembraneIsoform Gamma: Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Ectonucleoside Triphosphate Diphosphohydrolase 2 antibodyAnti-Ntpdase 2 antibodyAnti-Cd39 Antigen-Like 1 antibodyAnti-Ecto-Atp Diphosphohydrolase 2 antibodyAnti-Ecto-Atpdase 2 antibodyAnti-Ecto-Atpase 2 antibodyAnti-ENTPD2 antibodyAnti-CD39L1 antibody |
Information sourced from Uniprot.org
