| Host: |
Rabbit |
| Applications: |
ELISA/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ENTPD1 (440-490) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
FITC |
| Isotype: |
IgG |
| Formulation: |
Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: |
Affinity Purified |
| Concentration: |
0.5-1.5 µg/µl |
| Dilution Range: |
WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200IHC: 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
ENTPD1 |
| Gene ID: |
953 |
| Uniprot ID: |
ENTP1_HUMAN |
| Immunogen Region: |
440-490 |
| Immunogen: |
Synthetic peptide taken within amino acid region 440-490 on human EctoNucleoside TriPhosphate Diphosphohydrolase 1. |
| Tissue Specificity | Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Highly expressed in placenta, lung, skeletal muscle, kidney. |
| Post Translational Modifications | N-glycosylated. The N-terminus is blocked. Palmitoylated on Cys-13.which is required for caveola targeting. |
| Function | Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow. |
| Protein Name | Ectonucleoside Triphosphate Diphosphohydrolase 1Atp DiphosphohydrolaseAtp-DphAtpdaseEcto-Atp Diphosphohydrolase 1Ecto-Atpdase 1Ecto-Atpase 1Ecto-ApyraseLymphoid Cell Activation AntigenNucleoside Triphosphate Diphosphohydrolase 1Ntpdase1Cd Antigen Cd39 |
| Database Links | Reactome: R-HSA-8850843Reactome: R-HSA-9660826 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCaveola |
| Alternative Antibody Names | Anti-Ectonucleoside Triphosphate Diphosphohydrolase 1 antibodyAnti-Atp Diphosphohydrolase antibodyAnti-Atp-Dph antibodyAnti-Atpdase antibodyAnti-Ecto-Atp Diphosphohydrolase 1 antibodyAnti-Ecto-Atpdase 1 antibodyAnti-Ecto-Atpase 1 antibodyAnti-Ecto-Apyrase antibodyAnti-Lymphoid Cell Activation Antigen antibodyAnti-Nucleoside Triphosphate Diphosphohydrolase 1 antibodyAnti-Ntpdase1 antibodyAnti-Cd Antigen Cd39 antibodyAnti-ENTPD1 antibodyAnti-CD39 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
