Anti-ENO1/Alpha-enolase antibody (Met1-Lys434) [1A067] (STJA0021905)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenMammalian cells-derived recombinant Human ENO1/Alpha-enolase (Met1-Lys434)
General Information
| Short Description | Mouse monoclonal Alpha-Enolase (Met1-Lys434) antibody for use in ELISA, IHC and WB in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IHC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1A067 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | ENO1 |
| Gene ID | 2023 |
| Uniprot ID | ENOA_HUMAN |
| Immunogen | Mammalian cells-derived recombinant Human ENO1/Alpha-enolase (Met1-Lys434) |
| Immunogen Region | Met1-Lys434 |
Additional Info
| Post Translational Modifications | ISGylated. Lysine 2-hydroxyisobutyrylation (Khib) by p300/EP300 activates the phosphopyruvate hydratase activity. |
| Function | Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. Isoform MBP-1: Binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor. |
| Protein Name | Alpha-Enolase2-Phospho-D-Glycerate Hydro-LyaseC-Myc Promoter-Binding ProteinEnolase 1Mbp-1Mpb-1Non-Neural EnolaseNnePhosphopyruvate HydratasePlasminogen-Binding Protein |
| Database Links | Reactome: R-HSA-70171Reactome: R-HSA-70263Reactome: R-HSA-9636667 |
| Cellular Localisation | CytoplasmCell MembraneMyofibrilSarcomereM LineCan Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) FormEno1 Is Localized To The M LineIsoform Mbp-1: Nucleus |
| Alternative Antibody Names | Anti-Alpha-Enolase antibodyAnti-2-Phospho-D-Glycerate Hydro-Lyase antibodyAnti-C-Myc Promoter-Binding Protein antibodyAnti-Enolase 1 antibodyAnti-Mbp-1 antibodyAnti-Mpb-1 antibodyAnti-Non-Neural Enolase antibodyAnti-Nne antibodyAnti-Phosphopyruvate Hydratase antibodyAnti-Plasminogen-Binding Protein antibodyAnti-ENO1 antibodyAnti-ENO1L1 antibodyAnti-MBPB1 antibodyAnti-MPB1 antibody |
Information sourced from Uniprot.org