Endothelin Receptor B antibody western blot 293T STJA0036331

Anti-Endothelin Receptor B antibody [R02-8J4] (STJA0036331)

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STJA0036331
£133.50 - £281.50
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Short Description :Rabbit monoclonal anti-Endothelin Receptor B for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IP
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R02-8J4
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:WB 1:500-1:1000
IP 1:50
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:EDNRB
Gene ID:1910
Uniprot ID:EDNRB_HUMAN
Immunogen:A synthesized peptide derived from human Endothelin B Receptor
Tissue Specificity Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells.
Post Translational Modifications Palmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405.
Function Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Name Endothelin Receptor Type B
Et-B
Et-Br
Endothelin Receptor Non-Selective Type
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-9856649
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Internalized After Activation By Endothelins
Alternative Antibody Names Anti-Endothelin Receptor Type B antibody
Anti-Et-B antibody
Anti-Et-Br antibody
Anti-Endothelin Receptor Non-Selective Type antibody
Anti-EDNRB antibody
Anti-ETRB antibody

Information sourced from Uniprot.org

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