Anti-EML4 antibody (398-448 aa) (STJ195558)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human EMAL4 at the amino acid range 398-448
General Information
| Short Description | Rabbit polyclonal anti-Echinoderm microtubule-associated protein-like 4 (398-448 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EML4 |
| Gene ID | 27436 |
| Uniprot ID | EMAL4_HUMAN |
| Immunogen | Synthesized peptide derived from the human EMAL4 at the amino acid range 398-448 |
| Immunogen Region | 398-448 aa |
| Specificity | This antibody detects endogenous levels of EMAL4 at Human/Mouse |
Additional Info
| Function | Essential for the formation and stability of microtubules (MTs). Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs. Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression. |
| Protein Name | Echinoderm Microtubule-Associated Protein-Like 4Emap-4Restrictedly Overexpressed Proliferation-Associated ProteinRopp 120 |
| Database Links | Reactome: R-HSA-9648025Reactome: R-HSA-9700645Reactome: R-HSA-9725370 |
| Cellular Localisation | CytoplasmCytoskeletonSpindleMicrotubule Organizing CenterMidbodyLocalizes To Microtubules (Mts) During Interphase With A Significantly Reduced Affinity For Mts During Mitosis |
| Alternative Antibody Names | Anti-Echinoderm Microtubule-Associated Protein-Like 4 antibodyAnti-Emap-4 antibodyAnti-Restrictedly Overexpressed Proliferation-Associated Protein antibodyAnti-Ropp 120 antibodyAnti-EML4 antibodyAnti-C2orf2 antibodyAnti-EMAPL4 antibody |
Information sourced from Uniprot.org