Anti-EML1 antibody (STJA0008236)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human EML1
General Information
| Short Description | Rabbit polyclonal anti-Echinoderm microtubule-associated protein-like 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EML1 |
| Gene ID | 2009 |
| Uniprot ID | EMAL1_HUMAN |
| Immunogen | Synthesized peptide derived from human EML1 |
| Specificity | This antibody detects endogenous levels of EML1 at Human, Mouse, Rat |
Additional Info
| Function | Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se. |
| Protein Name | Echinoderm Microtubule-Associated Protein-Like 1Emap-1Huemap-1 |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonDetected In Cytoplasmic PunctaeCo-Localizes With MicrotubulesEnriched In Perinuclear Regions During Interphase And In The Region Of Spindle Microtubules During MetaphaseEnriched At The Midzone During Telophase And CytokinesisDetected At Growth Cones In Neurons |
| Alternative Antibody Names | Anti-Echinoderm Microtubule-Associated Protein-Like 1 antibodyAnti-Emap-1 antibodyAnti-Huemap-1 antibodyAnti-EML1 antibodyAnti-EMAP1 antibodyAnti-EMAPL antibodyAnti-EMAPL1 antibody |
Information sourced from Uniprot.org