| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ELP5 (17-316) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ELP5 |
| Gene ID: |
23587 |
| Uniprot ID: |
ELP5_HUMAN |
| Immunogen Region: |
17-316 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 17-316 of human ELP5 (NP_056177.3). |
| Immunogen Sequence: |
MLDSLLALGGLVLLRDSVEW EGRSLLKALVKKSALCGEQV HILGCEVSEEEFREGFDSDI NNRLVYHDFFRDPLNWSKTE EAFPGGPLGALRAMCKRTDP VPVTIALDSLSWLLLRLPCT TLCQVLHAVSHQDSCPGDSS SVGKVSVLGLLHEELHGPGP VGALSSLAQTEVTLGGTMGQ ASAHILCRRPRQRPTDQTQW FSILPDFSLDLQEGPSVESQ PYSDPHIPPVDPTTHLTFN |
| Tissue Specificity | Ubiquitously expressed with high levels in heart, brain, liver, skeletal muscle and testis. |
| Post Translational Modifications | Tyrosine-phosphorylated. |
| Function | Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Involved in cell migration. |
| Protein Name | Elongator Complex Protein 5Dermal Papilla-Derived Protein 6S-Phase 2 Protein |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Elongator Complex Protein 5 antibodyAnti-Dermal Papilla-Derived Protein 6 antibodyAnti-S-Phase 2 Protein antibodyAnti-ELP5 antibodyAnti-C17orf81 antibodyAnti-DERP6 antibodyAnti-HSPC002 antibodyAnti-MSTP071 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
