Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Elongation of very long chain fatty acids protein 2 (250-296 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ELOVL2 |
Gene ID: |
54898 |
Uniprot ID: |
ELOV2_HUMAN |
Immunogen Region: |
250-296 aa |
Specificity: |
ELOVL2 Polyclonal Antibody detects endogenous levels of ELOVL2 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ELOVL2 at the amino acid range 250-296 |
Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
Protein Name | Elongation Of Very Long Chain Fatty Acids Protein 23-Keto Acyl-Coa Synthase Elovl2Elovl Fatty Acid Elongase 2Elovl Fa Elongase 2Very Long Chain 3-Ketoacyl-Coa Synthase 2Very Long Chain 3-Oxoacyl-Coa Synthase 2 |
Database Links | Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Elongation Of Very Long Chain Fatty Acids Protein 2 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl2 antibodyAnti-Elovl Fatty Acid Elongase 2 antibodyAnti-Elovl Fa Elongase 2 antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 2 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 2 antibodyAnti-ELOVL2 antibodyAnti-ELG3 antibodyAnti-SSC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance