Anti-ELOVL1 antibody (148-198) {FITC} (STJ500872)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1.
General Information
| Short Description | Rabbit polyclonal antibody anti-ELOVL1 (148-198) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.5 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500ELISA: 1:10, 000IP: 1:200IHC: 1:100 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ELOVL1 |
| Gene ID | 64834 |
| Uniprot ID | ELOV1_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1. |
| Immunogen Region | 148-198 |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs. |
| Protein Name | Very Long Chain Fatty Acid Elongase 13-Keto Acyl-Coa Synthase Elovl1Elovl Fatty Acid Elongase 1Elovl Fa Elongase 1Elongation Of Very Long Chain Fatty Acids Protein 1Very Long Chain 3-Ketoacyl-Coa Synthase 1Very Long Chain 3-Oxoacyl-Coa Synthase 1 |
| Database Links | Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very Long Chain Fatty Acid Elongase 1 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl1 antibodyAnti-Elovl Fatty Acid Elongase 1 antibodyAnti-Elovl Fa Elongase 1 antibodyAnti-Elongation Of Very Long Chain Fatty Acids Protein 1 antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 1 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 1 antibodyAnti-ELOVL1 antibodyAnti-SSC1 antibodyAnti-CGI-88 antibody |
Information sourced from Uniprot.org