Anti-ELMO3 antibody (504-773) (STJ29262)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ELMO3 (504-773) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ELMO3 |
| Gene ID | 79767 |
| Uniprot ID | ELMO3_HUMAN |
| Immunogen Region | 504-773 |
| Immunogen Sequence | NKTWKEMRATQEDFDKVMQV VREQLARTLALKPTSLELFR TKVNALTYGEVLRLRQTERL HQEGTLAPPILELREKLKPE LMGLIRQQRLLRLCEGTLFR KISSRRRQDKLWFCCLSPNH KLLQYGDMEEGASPPTLESL PEQLPVADMRALLTGKDCPH VREKGSGKQNKDLYELAFSI SYDRGEEEAYLNFIAPSKRE FYLWTDGLSALLGSPMGSEQ TRLDLEQLLTMETKLRLLE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 504-773 of human ELMO3 (NP_078988.2). |
Additional Info
| Function | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. |
| Protein Name | Engulfment And Cell Motility Protein 3 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Engulfment And Cell Motility Protein 3 antibodyAnti-ELMO3 antibody |
Information sourced from Uniprot.org