Anti-ELKS/RAB6IP2 antibody (N-Term) (STJ70263)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-ELKS/RAB6IP2 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx. 90kDa band observed in Human Pancreas lysates (calculated MW of 82.0kDa according to NP_829882.1). Recommended concentration: 0.1-0.3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | ERC1 |
| Gene ID | 23085 |
| Uniprot ID | RB6I2_HUMAN |
| Accession Number | NP_829883.1; NP_829884.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | YGSARSVGKVEPS |
| Specificity | This antibody is expected to recognize all reported isoforms (NP_829883.1; NP_829884.1). |
Additional Info
| Function | Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. |
| Protein Name | Elks/Rab6-Interacting/Cast Family Member 1Erc-1Rab6-Interacting Protein 2 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeMembranePeripheral Membrane ProteinGolgi Apparatus MembranePresynaptic Cell MembraneCell ProjectionPodosomeRecruited On Golgi Membranes By Rab6a In A Gtp-Dependent MannerLocalized To The Cortex Of Myotube Podosomes |
| Alternative Antibody Names | Anti-Elks/Rab6-Interacting/Cast Family Member 1 antibodyAnti-Erc-1 antibodyAnti-Rab6-Interacting Protein 2 antibodyAnti-ERC1 antibodyAnti-ELKS antibodyAnti-KIAA1081 antibodyAnti-RAB6IP2 antibody |
Information sourced from Uniprot.org