Anti-ELF2 antibody (1-140) (STJ29623)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ELF2 (1-140) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ELF2 |
| Gene ID | 1998 |
| Uniprot ID | ELF2_HUMAN |
| Immunogen Region | 1-140 |
| Immunogen Sequence | MATSLHEGPTNQLDLLIRAV EASVHSSNAHCTDKTIEAAE ALLHMESPTCLRDSRSPVEV FVPPCVSTPEFIHAAMRPDV ITETVVEVSTEESEPMDTSP IPTSPDSHEPMKKKKVGRKP KTQQSPISNGSPELGIKKKP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ELF2 (NP_006865.1). |
Additional Info
| Tissue Specificity | Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes. |
| Function | Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter. Isoform 2 may function in repression of RUNX1-mediated transactivation. |
| Protein Name | Ets-Related Transcription Factor Elf-2E74-Like Factor 2New Ets-Related Factor |
| Database Links | Reactome: R-HSA-8939245 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ets-Related Transcription Factor Elf-2 antibodyAnti-E74-Like Factor 2 antibodyAnti-New Ets-Related Factor antibodyAnti-ELF2 antibodyAnti-NERF antibody |
Information sourced from Uniprot.org