| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Zinc phosphodiesterase ELAC protein 2 (161-210 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ELAC2 |
| Gene ID: | 60528 |
| Uniprot ID: | RNZ2_HUMAN |
| Immunogen Region: | 161-210 aa |
| Specificity: | RNase Z2 Polyclonal Antibody detects endogenous levels of RNase Z2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ELAC2 at the amino acid range 161-210 |
| Function | Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly. |
| Protein Name | Zinc Phosphodiesterase Elac Protein 2Elac Homolog Protein 2Heredity Prostate Cancer Protein 2Ribonuclease Z 2Rnase Z 2Trna 3 Endonuclease 2Trnase Z 2 |
| Database Links | Reactome: R-HSA-6784531Reactome: R-HSA-6785470Reactome: R-HSA-8868766Reactome: R-HSA-9708296 |
| Cellular Localisation | MitochondrionMitochondrion MatrixMitochondrion NucleoidNucleusMainly Mitochondrial |
| Alternative Antibody Names | Anti-Zinc Phosphodiesterase Elac Protein 2 antibodyAnti-Elac Homolog Protein 2 antibodyAnti-Heredity Prostate Cancer Protein 2 antibodyAnti-Ribonuclease Z 2 antibodyAnti-Rnase Z 2 antibodyAnti-Trna 3 Endonuclease 2 antibodyAnti-Trnase Z 2 antibodyAnti-ELAC2 antibodyAnti-HPC2 antibody |
Information sourced from Uniprot.org
