Anti-ELAC1 antibody (STJA0004778)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human ELAC1
General Information
| Short Description | Rabbit polyclonal anti-Zinc Phosphodiesterase Elac Protein 1 for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.14 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:50-1:300 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ELAC1 |
| Gene ID | 55520 |
| Uniprot ID | RNZ1_HUMAN |
| Immunogen | Fusion protein of human ELAC1 |
Additional Info
| Tissue Specificity | Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Function | Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1. |
| Protein Name | Zinc Phosphodiesterase Elac Protein 1Deleted In Ma29Elac Homolog Protein 1Ribonuclease Z 1Rnase Z 1Trna 3 Endonuclease 1Trnase Z 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolNucleusMainly Cytosolic |
| Alternative Antibody Names | Anti-Zinc Phosphodiesterase Elac Protein 1 antibodyAnti-Deleted In Ma29 antibodyAnti-Elac Homolog Protein 1 antibodyAnti-Ribonuclease Z 1 antibodyAnti-Rnase Z 1 antibodyAnti-Trna 3 Endonuclease 1 antibodyAnti-Trnase Z 1 antibodyAnti-ELAC1 antibodyAnti-D29 antibody |
Information sourced from Uniprot.org