Anti-eIF5A/eIF5A2 antibody (STJ194756)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human eIF5A/eIF5A2
General Information
| Short Description | Rabbit polyclonal anti-Eukaryotic translation initiation factor 5A-1 and Eukaryotic translation initiation factor 5A-2 for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA-Pep 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EIF5A2EIF5A |
| Gene ID | 566481984 |
| Uniprot ID | IF5A2_HUMANIF5A1_HUMAN |
| Immunogen | Synthesized peptide derived from the human eIF5A/eIF5A2 |
| Specificity | This antibody detects endogenous levels of human eIF5A/eIF5A2 |
Additional Info
| Tissue Specificity | Expressed in umbilical vein endothelial cells and several cancer cell lines (at protein level). |
| Post Translational Modifications | Acetylated. Deacetylated by SIRT2. eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine). |
| Database Links | Reactome: R-HSA-204626 |
| Cellular Localisation | CytoplasmNucleusEndoplasmic Reticulum MembranePeripheral Membrane ProteinCytoplasmic SideNuclear Pore ComplexHypusine Modification Promotes The Nuclear Export And Cytoplasmic Localization And There Was A Dynamic Shift In The Localization From Predominantly Cytoplasmic To Primarily Nuclear Under Apoptotic Inducing Conditions |
| Protein Name | Eukaryotic Translation Initiation Factor 5a-1Eif-5a-1Eif-5a1Eukaryotic Initiation Factor 5a Isoform 1Eif-5aRev-Binding FactorEif-4d |
| Alternative Names | Anti-Eukaryotic Translation Initiation Factor 5a-1 antibodyAnti-Eif-5a-1 antibodyAnti-Eif-5a1 antibodyAnti-Eukaryotic Initiation Factor 5a Isoform 1 antibodyAnti-Eif-5a antibodyAnti-Rev-Binding Factor antibodyAnti-Eif-4d antibodyAnti-EIF5A antibody |
Information sourced from Uniprot.org