| Short Description : | Rabbit polyclonal EIF4G2 (320-490) antibody for use in WB, IHC-P, IF, ICC, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/IP/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specif |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EIF4G2 |
| Gene ID: | 1982 |
| Uniprot ID: | IF4G2_HUMAN |
| Immunogen Region: | 320-490 |
| Immunogen Sequence: | PKTINQIRQDAVKDLGVFIP APMAQGMRSDFFLEGPFMPP RMKMDRDPLGGLADMFGQMP GSGIGTGPGVIQDRFSPTMG RHRSNQLFNGHGGHIMPPTQ SQFGEMGGKFMKSQGLSQLY HNQSQGLLSQLQGQSKDMPP RFSKKGQLNADEISLRPAQS FLMNKNQVPKL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 320-490 of human EIF4G2/p97 (NP_001409.3). |
| Tissue Specificity | Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney. |
| Post Translational Modifications | Phosphorylation.hyperphosphorylated during mitosis. |
| Function | Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. |
| Protein Name | Eukaryotic Translation Initiation Factor 4 Gamma 2Eif-4-Gamma 2Eif-4g 2Eif4g 2Death-Associated Protein 5Dap-5P97 |
| Database Links | Reactome: R-HSA-1169408 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Eukaryotic Translation Initiation Factor 4 Gamma 2 antibodyAnti-Eif-4-Gamma 2 antibodyAnti-Eif-4g 2 antibodyAnti-Eif4g 2 antibodyAnti-Death-Associated Protein 5 antibodyAnti-Dap-5 antibodyAnti-P97 antibodyAnti-EIF4G2 antibodyAnti-DAP5 antibodyAnti-OK antibodyAnti-SW-cl.75 antibody |
Information sourced from Uniprot.org
