| Host: |
Mouse |
| Applications: |
WB |
| Reactivity: |
Transfected |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Eukaryotic translation initiation factor 4E-binding protein 3 is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
3B6-D3-H7 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EIF4EBP3 |
| Gene ID: |
8637 |
| Uniprot ID: |
4EBP3_HUMAN |
| Specificity: |
Transfected Only. |
| Immunogen: |
Recombinant protein of human EIF4EBP3. |
| Post Translational Modifications | Phosphorylated. |
| Function | Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: the hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repression of translation. In contrast, the hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Inhibits EIF4E-mediated mRNA nuclear export. |
| Protein Name | Eukaryotic Translation Initiation Factor 4e-Binding Protein 34e-Bp3Eif4e-Binding Protein 3 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Eukaryotic Translation Initiation Factor 4e-Binding Protein 3 antibodyAnti-4e-Bp3 antibodyAnti-Eif4e-Binding Protein 3 antibodyAnti-EIF4EBP3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
