Anti-EIF4A2 antibody (N-Term) (STJA0003625)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide from the N-terminal region of the human eIF4A2 protein.
General Information
| Short Description | Rabbit polyclonal anti-eIF4A2 (N-Term) for use in WB in Human, Mouse, Bovine, Non-Human Primates and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Bovine/Non-Human Primates/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range | WB 1:1000 |
| Formulation | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EIF4A2 |
| Gene ID | 1974 |
| Uniprot ID | IF4A2_HUMAN |
| Immunogen | Synthetic peptide from the N-terminal region of the human eIF4A2 protein. |
| Immunogen Region | N-Term |
Additional Info
| Function | ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. |
| Protein Name | Eukaryotic Initiation Factor 4a-IiEif-4a-IiEif4a-IiAtp-Dependent Rna Helicase Eif4a-2 |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-156827Reactome: R-HSA-429947Reactome: R-HSA-72649Reactome: R-HSA-72662Reactome: R-HSA-72702Reactome: R-HSA-72706Reactome: R-HSA-9820841Reactome: R-HSA-9820865 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Eukaryotic Initiation Factor 4a-Ii antibodyAnti-Eif-4a-Ii antibodyAnti-Eif4a-Ii antibodyAnti-Atp-Dependent Rna Helicase Eif4a-2 antibodyAnti-EIF4A2 antibodyAnti-DDX2B antibodyAnti-EIF4F antibody |
Information sourced from Uniprot.org