Anti-EIF2A antibody (480-494 aa) [R08-8E2] (STJA0011265)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human eIF2A
General Information
| Short Description | Rabbit monoclonal anti-eIF2A (480-494 aa) for use in WB, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-8E2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | EIF2A |
| Gene ID | 83939 |
| Uniprot ID | EIF2A_HUMAN |
| Immunogen | A synthetic peptide of human eIF2A |
| Immunogen Region | 480-494 aa |
Additional Info
| Tissue Specificity | Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta. |
| Function | Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. |
| Protein Name | Eukaryotic Translation Initiation Factor 2aEif-2a65 Kda Eukaryotic Translation Initiation Factor 2a Cleaved Into - Eukaryotic Translation Initiation Factor 2a - N-Terminally Processed |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Eukaryotic Translation Initiation Factor 2a antibodyAnti-Eif-2a antibodyAnti-65 Kda Eukaryotic Translation Initiation Factor 2a Cleaved Into - Eukaryotic Translation Initiation Factor 2a - N-Terminally Processed antibodyAnti-EIF2A antibodyAnti-CDA02 antibodyAnti-MSTP004 antibodyAnti-MSTP089 antibody |
Information sourced from Uniprot.org