Anti-EHF antibody (STJA0007742)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human EHF
General Information
| Short Description | Rabbit polyclonal anti-ETS homologous factor for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EHF |
| Gene ID | 26298 |
| Uniprot ID | EHF_HUMAN |
| Immunogen | Synthesized peptide derived from human EHF |
| Specificity | This antibody detects endogenous levels of EHF at Human, Mouse |
Additional Info
| Function | Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter. May contribute to development and carcinogenesis by acting as a tumor suppressor gene or anti-oncogene. |
| Protein Name | Ets Homologous FactorHehfEts Domain-Containing Transcription FactorEpithelium-Specific Ets Transcription Factor 3Ese-3 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ets Homologous Factor antibodyAnti-Hehf antibodyAnti-Ets Domain-Containing Transcription Factor antibodyAnti-Epithelium-Specific Ets Transcription Factor 3 antibodyAnti-Ese-3 antibodyAnti-EHF antibodyAnti-ESE3 antibodyAnti-ESE3B antibodyAnti-ESEJ antibody |
Information sourced from Uniprot.org