Anti-EHD2 antibody (STJA0007380)

SKU:
STJA0007380

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EH domain-containing protein 2 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EHD2
Gene ID: 30846
Uniprot ID: EHD2_HUMAN
Specificity: This antibody detects endogenous levels of EHD2 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human EHD2
Function ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane.
Protein Name Eh Domain-Containing Protein 2
Past Homolog 2
Database Links Reactome: R-HSA-983231
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Membrane
Caveola
Endosome Membrane
Cytoplasm
Cytosol
Colocalizes With Glut4 In Intracellular Tubulovesicular Structures That Are Associated With Cortical F-Actin
Colocalizes With Fer1l5 At Plasma Membrane In Myoblasts And Myotubes
Alternative Antibody Names Anti-Eh Domain-Containing Protein 2 antibody
Anti-Past Homolog 2 antibody
Anti-EHD2 antibody
Anti-PAST2 antibody

Information sourced from Uniprot.org

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