Anti-EGF antibody (977-1029 aa) [SRM5455] (STJ11107369)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal EGF (977-1029 aa) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5455 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Egf |
| Gene ID | 13645 |
| Uniprot ID | EGF_MOUSE |
| Immunogen Region | 977-1029 aa |
| Immunogen Sequence | NSYPGCPSSYDGYCLNGGVC MHIESLDSYTCNCVIGYSGD RCQTRDLRWWELR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 977-1029 of mouse EGF (NP_034243.2). |
Additional Info
| Function | EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. |
| Protein Name | Pro-Epidermal Growth FactorEgf Cleaved Into - Epidermal Growth Factor |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-1227986Reactome: -MMU-1236394Reactome: -MMU-1250196Reactome: -MMU-1257604Reactome: -MMU-177929Reactome: -MMU-179812Reactome: -MMU-180292Reactome: -MMU-180336Reactome: -MMU-182971Reactome: -MMU-1963642Reactome: -MMU-212718Reactome: -MMU-5673001Reactome: -MMU-6785631Reactome: -MMU-6811558Reactome: -MMU-8847993Reactome: -MMU-8856825Reactome: -MMU-8856828Reactome: -MMU-8863795Reactome: -MMU-9009391Reactome: -MMU-9013507 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Pro-Epidermal Growth Factor antibodyAnti-Egf Cleaved Into - Epidermal Growth Factor antibodyAnti-Egf antibody |
Information sourced from Uniprot.org