Anti-EG VEGF antibody [R04-6Z8] (STJA0037451)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human PROK1
General Information
| Short Description | Rabbit monoclonal anti-EG VEGF for use in WB and FC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-6Z8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PROK1 |
| Gene ID | 84432 |
| Uniprot ID | PROK1_HUMAN |
| Immunogen | A synthesized peptide derived from human PROK1 |
Additional Info
| Tissue Specificity | Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. |
| Function | Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. |
| Protein Name | Prokineticin-1Endocrine-Gland-Derived Vascular Endothelial Growth FactorEg-VegfMambakine |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Prokineticin-1 antibodyAnti-Endocrine-Gland-Derived Vascular Endothelial Growth Factor antibodyAnti-Eg-Vegf antibodyAnti-Mambakine antibodyAnti-PROK1 antibodyAnti-UNQ600 antibodyAnti-PRO1186 antibody |
Information sourced from Uniprot.org