Anti-EFTUD2 antibody (1-205 aa) [SRM5270] (STJ11107172)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal EFTUD2 (1-205 aa) antibody for use in WB, IHC-P, IF, ICC, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5270 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specif |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EFTUD2 |
| Gene ID | 9343 |
| Uniprot ID | U5S1_HUMAN |
| Immunogen Region | 1-205 aa |
| Immunogen Sequence | MDTDLYDEFGNYIGPELDSD EDDDELGRETKDLDEMDDDD DDDDVGDHDDDHPGMEVVLH EDKKYYPTAEEVYGPEVETI VQEEDTQPLTEPIIKPVKTK KFTLMEQTLPVTVYEMDFLA DLMDNSELIRNVTLCGHLHH GKTCFVDCLIEQTHPEIRKR YDQDLCYTDILFTEQERGVG IKSTPVTVVLPDTKGKSYLF NIMDT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human EFTUD2 (NP_004238.3). |
Additional Info
| Function | Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Protein Name | 116 Kda U5 Small Nuclear Ribonucleoprotein ComponentElongation Factor Tu Gtp-Binding Domain-Containing Protein 2Snu114 HomologHsnu114U5 Snrnp-Specific Protein - 116 KdaU5-116 Kda |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-116 Kda U5 Small Nuclear Ribonucleoprotein Component antibodyAnti-Elongation Factor Tu Gtp-Binding Domain-Containing Protein 2 antibodyAnti-Snu114 Homolog antibodyAnti-Hsnu114 antibodyAnti-U5 Snrnp-Specific Protein - 116 Kda antibodyAnti-U5-116 Kda antibodyAnti-EFTUD2 antibodyAnti-KIAA0031 antibodyAnti-SNRP116 antibody |
Information sourced from Uniprot.org