Anti-EFS antibody (60-190) (STJ118907)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal EFS (60-190) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EFS |
| Gene ID | 10278 |
| Uniprot ID | EFS_HUMAN |
| Immunogen Region | 60-190 |
| Immunogen Sequence | TALRVPSSGPYDCPASFSHP LTRVAPQPPGEDDAPYDVPL TPKPPAELEPDLEWEGGREP GPPIYAAPSNLKRASALLNL YEAPEELLADGEGGGTDEGI YDVPLLGPEAPPSPEPPGAL ASHDQDTLAQL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human EFS (NP_115835.1). |
Additional Info
| Tissue Specificity | The protein has been detected in lung and placenta. |
| Post Translational Modifications | Phosphorylated on multiple tyrosine residues. Phosphorylated on tyrosines by FYN and SRC. |
| Function | Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES. |
| Protein Name | Embryonal Fyn-Associated SubstrateHefsCas Scaffolding Protein Family Member 3 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Embryonal Fyn-Associated Substrate antibodyAnti-Hefs antibodyAnti-Cas Scaffolding Protein Family Member 3 antibodyAnti-EFS antibodyAnti-CASS3 antibody |
Information sourced from Uniprot.org