Anti-EFNA3 antibody (23-214) (STJ23481)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal EFNA3 (23-214) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EFNA3 |
| Gene ID | 1944 |
| Uniprot ID | EFNA3_HUMAN |
| Immunogen Region | 23-214 |
| Immunogen Sequence | QGPGGALGNRHAVYWNSSNQ HLRREGYTVQVNVNDYLDIY CPHYNSSGVGPGAGPGPGGG AEQYVLYMVSRNGYRTCNAS QGFKRWECNRPHAPHSPIKF SEKFQRYSAFSLGYEFHAGH EYYYISTPTHNLHWKCLRMK VFVCCASTSHSGEKPVPTLP QFTMGPNVKINVLEDFEGEN PQVPKLEKSISG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 23-214 of human EFNA3 (NP_004943.1). |
Additional Info
| Tissue Specificity | Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. |
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
| Protein Name | Ephrin-A3Efl-2Ehk1 LigandEhk1-LEph-Related Receptor Tyrosine Kinase Ligand 3Lerk-3 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Ephrin-A3 antibodyAnti-Efl-2 antibodyAnti-Ehk1 Ligand antibodyAnti-Ehk1-L antibodyAnti-Eph-Related Receptor Tyrosine Kinase Ligand 3 antibodyAnti-Lerk-3 antibodyAnti-EFNA3 antibodyAnti-EFL2 antibodyAnti-EPLG3 antibodyAnti-LERK3 antibody |
Information sourced from Uniprot.org