| Tissue Specificity | Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. |
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
| Protein Name | Ephrin-A3Efl-2Ehk1 LigandEhk1-LEph-Related Receptor Tyrosine Kinase Ligand 3Lerk-3 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Ephrin-A3 antibodyAnti-Efl-2 antibodyAnti-Ehk1 Ligand antibodyAnti-Ehk1-L antibodyAnti-Eph-Related Receptor Tyrosine Kinase Ligand 3 antibodyAnti-Lerk-3 antibodyAnti-EFNA3 antibodyAnti-EFL2 antibodyAnti-EPLG3 antibodyAnti-LERK3 antibody |
Information sourced from Uniprot.org
