| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-EFNA3 (23-214) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EFNA3 |
| Gene ID: |
1944 |
| Uniprot ID: |
EFNA3_HUMAN |
| Immunogen Region: |
23-214 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 23-214 of human EFNA3 (NP_004943.1). |
| Immunogen Sequence: |
QGPGGALGNRHAVYWNSSNQ HLRREGYTVQVNVNDYLDIY CPHYNSSGVGPGAGPGPGGG AEQYVLYMVSRNGYRTCNAS QGFKRWECNRPHAPHSPIKF SEKFQRYSAFSLGYEFHAGH EYYYISTPTHNLHWKCLRMK VFVCCASTSHSGEKPVPTLP QFTMGPNVKINVLEDFEGEN PQVPKLEKSISG |
| Tissue Specificity | Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. |
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
| Protein Name | Ephrin-A3Efl-2Ehk1 LigandEhk1-LEph-Related Receptor Tyrosine Kinase Ligand 3Lerk-3 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Ephrin-A3 antibodyAnti-Efl-2 antibodyAnti-Ehk1 Ligand antibodyAnti-Ehk1-L antibodyAnti-Eph-Related Receptor Tyrosine Kinase Ligand 3 antibodyAnti-Lerk-3 antibodyAnti-EFNA3 antibodyAnti-EFL2 antibodyAnti-EPLG3 antibodyAnti-LERK3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
