Anti-Cleaved-EFNA3-Gly214 antibody (214-215) (STJA0005859)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human EFNA3 (Cleaved-Gly214)
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Ephrin-A3-Gly214 (214-215) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:1000-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EFNA3 |
| Gene ID | 1944 |
| Uniprot ID | EFNA3_HUMAN |
| Immunogen | Synthesized peptide derived from human EFNA3 (Cleaved-Gly214) |
| Immunogen Region | 214-215 |
| Specificity | This antibody detects endogenous levels of Human, Mouse, Rat EFNA3 (Cleaved-Gly214, protein was cleaved amino acid sequence between 214-215 ) |
Additional Info
| Tissue Specificity | Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. |
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
| Protein Name | Ephrin-A3Efl-2Ehk1 LigandEhk1-LEph-Related Receptor Tyrosine Kinase Ligand 3Lerk-3 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Ephrin-A3 antibodyAnti-Efl-2 antibodyAnti-Ehk1 Ligand antibodyAnti-Ehk1-L antibodyAnti-Eph-Related Receptor Tyrosine Kinase Ligand 3 antibodyAnti-Lerk-3 antibodyAnti-EFNA3 antibodyAnti-EFL2 antibodyAnti-EPLG3 antibodyAnti-LERK3 antibody |
Information sourced from Uniprot.org