Anti-EFHD2 antibody (1-78) (STJ117125)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal EFHD2 (1-78) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EFHD2 |
| Gene ID | 79180 |
| Uniprot ID | EFHD2_HUMAN |
| Immunogen Region | 1-78 |
| Immunogen Sequence | MATDELATKLSRRLQMEGEG GGETPEQPGLNGAAAAAAGA PDEAAEALGSADCELSAKLL RRADLNQGIGEPQSPSRR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-78 of human EFHD2 (NP_077305.2). |
Additional Info
| Tissue Specificity | Found in lymphocytes.preferentially expressed in CD8+ cells. |
| Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| Protein Name | Ef-Hand Domain-Containing Protein D2Swiprosin-1 |
| Database Links | Reactome: R-HSA-9013405 |
| Cellular Localisation | Membrane RaftIn A Mouse Immature B-Cell Line Wehi-231 |
| Alternative Antibody Names | Anti-Ef-Hand Domain-Containing Protein D2 antibodyAnti-Swiprosin-1 antibodyAnti-EFHD2 antibodyAnti-SWS1 antibody |
Information sourced from Uniprot.org