Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-EFHD2 (1-78) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
EFHD2 |
Gene ID: |
79180 |
Uniprot ID: |
EFHD2_HUMAN |
Immunogen Region: |
1-78 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-78 of human EFHD2 (NP_077305.2). |
Immunogen Sequence: |
MATDELATKLSRRLQMEGEG GGETPEQPGLNGAAAAAAGA PDEAAEALGSADCELSAKLL RRADLNQGIGEPQSPSRR |
Tissue Specificity | Found in lymphocytes.preferentially expressed in CD8+ cells. |
Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
Protein Name | Ef-Hand Domain-Containing Protein D2Swiprosin-1 |
Database Links | Reactome: R-HSA-9013405 |
Cellular Localisation | Membrane RaftIn A Mouse Immature B-Cell Line Wehi-231 |
Alternative Antibody Names | Anti-Ef-Hand Domain-Containing Protein D2 antibodyAnti-Swiprosin-1 antibodyAnti-EFHD2 antibodyAnti-SWS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance