Anti-EEF2 antibody (STJ98488)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
ImmunogenPurified recombinant human EF-2 protein fragments expressed in E.coli.
General Information
| Short Description | Mouse monoclonal anti-Elongation factor 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity purification |
| Dilution Range | WB 1:1000-1:2000 |
| Formulation | Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EEF2 |
| Gene ID | 1938 |
| Uniprot ID | EF2_HUMAN |
| Immunogen | Purified recombinant human EF-2 protein fragments expressed in E.coli. |
| Specificity | EF-2 Monoclonal Antibody detects endogenous levels of EF-2 protein. |
Additional Info
| Function | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. |
| Protein Name | Elongation Factor 2Ef-2 |
| Database Links | Reactome: R-HSA-156902Reactome: R-HSA-5336415Reactome: R-HSA-5358493Reactome: R-HSA-6798695Reactome: R-HSA-8876725 |
| Cellular Localisation | CytoplasmNucleusPhosphorylation By Csk Promotes Cleavage And Sumoylation-Dependent Nuclear Translocation Of The C-Terminal Cleavage Product |
| Alternative Antibody Names | Anti-Elongation Factor 2 antibodyAnti-Ef-2 antibodyAnti-EEF2 antibodyAnti-EF2 antibody |
Information sourced from Uniprot.org