| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EEF1B2 |
| Gene ID: | 1933 |
| Uniprot ID: | EF1B_HUMAN |
| Immunogen Region: | 1-225 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human EEF1B2 (NP_001032752.1). |
| Immunogen Sequence: | MGFGDLKSPAGLQVLNDYLA DKSYIEGYVPSQADVAVFEA VSSPPPADLCHALRWYNHIK SYEKEKASLPGVKKALGKYG PADVEDTTGSGATDSKDDDD IDLFGSDDEEESEEAKRLRE ERLAQYESKKAKKPALVAKS SILLDVKPWDDETDMAKLEE CVRSIQADGLVWGSSKLVPV GYGIKKLQIQCVVEDDKVGT DMLEEQITAFEDYVQSMDVA AFNKI |
| Post Translational Modifications | Phosphorylation affects the GDP/GTP exchange rate. |
| Function | Catalytic subunit of the guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) of the eukaryotic elongation factor 1 complex (eEF1). Stimulates the exchange of GDP for GTP on elongation factor 1A (eEF1A), probably by displacing GDP from the nucleotide binding pocket in eEF1A. |
| Protein Name | Elongation Factor 1-BetaEf-1-BetaEef-1b Alpha |
| Database Links | Reactome: R-HSA-156842 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Elongation Factor 1-Beta antibodyAnti-Ef-1-Beta antibodyAnti-Eef-1b Alpha antibodyAnti-EEF1B2 antibodyAnti-EEF1B antibodyAnti-EF1B antibody |
Information sourced from Uniprot.org
